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gaba b receptor antagonist cgp 35348  (Tocris)


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    Tocris gaba b receptor antagonist cgp 35348
    Gaba B Receptor Antagonist Cgp 35348, supplied by Tocris, used in various techniques. Bioz Stars score: 94/100, based on 179 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/gaba+b+receptor+antagonist+cgp+35348/CGP+35348/bio_rxiv__2025__09__25__678558-185-8-19
    Average 94 stars, based on 179 article reviews
    gaba b receptor antagonist cgp 35348 - by Bioz Stars, 2026-11
    94/100 stars

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    Related Articles

    Mouse Assay:

    Article Title: Context-dependent presynaptic inhibition of somatostatin interneuron inputs to Layer 1 of the visual cortex
    Article Snippet: .. Mice received a single intraperitoneal injection of the GABA B receptor antagonist CGP-35348 (0.5 mg/kg in saline, 10 mL/kg) (Tocris Bioscience, 1245/10) in order to block GABA B receptor signaling pharmacologically . ..

    Injection:

    Article Title: Context-dependent presynaptic inhibition of somatostatin interneuron inputs to Layer 1 of the visual cortex
    Article Snippet: .. Mice received a single intraperitoneal injection of the GABA B receptor antagonist CGP-35348 (0.5 mg/kg in saline, 10 mL/kg) (Tocris Bioscience, 1245/10) in order to block GABA B receptor signaling pharmacologically . ..

    Saline:

    Article Title: Context-dependent presynaptic inhibition of somatostatin interneuron inputs to Layer 1 of the visual cortex
    Article Snippet: .. Mice received a single intraperitoneal injection of the GABA B receptor antagonist CGP-35348 (0.5 mg/kg in saline, 10 mL/kg) (Tocris Bioscience, 1245/10) in order to block GABA B receptor signaling pharmacologically . ..

    Blocking Assay:

    Article Title: Context-dependent presynaptic inhibition of somatostatin interneuron inputs to Layer 1 of the visual cortex
    Article Snippet: .. Mice received a single intraperitoneal injection of the GABA B receptor antagonist CGP-35348 (0.5 mg/kg in saline, 10 mL/kg) (Tocris Bioscience, 1245/10) in order to block GABA B receptor signaling pharmacologically . ..



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    Image Search Results


    GABA-inhibited HCC migration and invasion via GABAA receptor. A, B: Migration and invasion assays were performed in SK-Hep1 and SMMC-7721 cells stimulated with 10 µM GABA A or GABA B receptor agonists for 24 h. Bac, baclofen. The results show the quantification of 5 randomly selected fields. C, D: Migration and invasion assays were performed in SK-Hep1 and SMMC-7721 cells stimulated with 10 µM GABA for 24 h with or without 2 h pre-incubation with GABA A or GABA B receptors antagonists. CGP, CGP 35348 hydrate. Data are representative of three independent experiments and are shown as means ±SEM (*, P <0.05, **, P <0.01, by Student’s t -test).

    Journal: Cancer Biology & Medicine

    Article Title: Suppression of Human Liver Cancer Cell Migration and Invasion via the GABA A Receptor

    doi: 10.3969/j.issn.2095-3941.2012.02.002

    Figure Lengend Snippet: GABA-inhibited HCC migration and invasion via GABAA receptor. A, B: Migration and invasion assays were performed in SK-Hep1 and SMMC-7721 cells stimulated with 10 µM GABA A or GABA B receptor agonists for 24 h. Bac, baclofen. The results show the quantification of 5 randomly selected fields. C, D: Migration and invasion assays were performed in SK-Hep1 and SMMC-7721 cells stimulated with 10 µM GABA for 24 h with or without 2 h pre-incubation with GABA A or GABA B receptors antagonists. CGP, CGP 35348 hydrate. Data are representative of three independent experiments and are shown as means ±SEM (*, P <0.05, **, P <0.01, by Student’s t -test).

    Article Snippet: GABA, gaboxadol hydrochloride (T101, GABA A receptor agonist, 10 µM), muscimol hydrobromide (GABA A receptor agonist, 10 µM), 1(S), 9(R)-(−)-bicuculline methbromide (B7561, GABA A receptor antagonist, 10 µM), SR-95531 (S106, GABA A receptor antagonist, 10 µM), CGP 35348 hydrate (C5851, GABA B receptor antagonist, 10 µM), and 2-hydroxysaclofenwere (A6566, GABA B receptor antagonist, 10 µM) were obtained from Sigma-Aldrich and dissolved in H 2 O. (±)-Baclofen (GABA B receptor agonist, 10 µM) (Sigma-Aldrich) was dissolved in dimethyl sulfoxide (DMSO)/1 M HCl.

    Techniques: Migration, Incubation